德晋贵宾厅

    B-hEMP2 mice

    C57BL/6-Emp2tm1(EMP2)Bcgen/Bcgen • 111358

    B-hEMP2 mice

    Product nameB-hEMP2 mice
    Catalog number111358
    Strain nameC57BL/6-Emp2tm1(EMP2)Bcgen/Bcgen
    Strain backgroundC57BL/6
    NCBI gene ID2013 (Human)
    AliasesXMP

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    • Targeting strategy
    • Phenotypic analysis

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        Targeting strategy

        Gene targeting strategy for B-hEMP2 mice. The exons 2-5 of mouse Emp2 gene that encodes the full-length protein was replaced by human EMP2 exons 2-5 in B-hEMP2 mice.

        mRNA expression analysis
        Strain specific analysis of EMP2 gene expression in wild-type C57BL/6 mice and B-hEMP2 mice by RT-PCR. Mouse Emp2 mRNA was detectable only in the lung of wild-type C57BL/6 mice (+/+). Human EMP2 mRNA was detectable only in homozygous B-hEMP2 mice (H/H), but not in wild-type mice.
        * When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hEMP2 mice] (Cat# 111358) was purchased from Biocytogen.