C57BL/6-Klrd1tm1(KLRD1)Bcgen/Bcgen • 110044
| Product name | B-hCD94 mice |
|---|---|
| Catalog number | 110044 |
| Strain name | C57BL/6-Klrd1tm1(KLRD1)Bcgen/Bcgen |
| Strain background | C57BL/6 |
| NCBI gene ID | 3824 (Human) |
| Aliases | CD94 |
Gene targeting strategy for B-hCD94 mice. The exon 3~6 of mouse Klrd1 gene that encode the extracellular domain were replaced by human KLRD1 exon 3~6 in B-hCD94 mice.
Strain specific CD94 expression analysis in homozygous B-hCD94 mice by flow cytometry. Splenocytes were collected from WT and heterozygous B-hCD94 (H/+) mice, and analyzed by flow cytometry with species-specific anti-CD94 antibody. Mouse CD94 was detectable in WT and heterozygous B-hCD94 (H/+) mice. Human CD94 was exclusively detectable in heterozygous B-hCD94 but not WT mice.
